What is Diabetes Mellitus?
Diabetes is a lifelong (chronic) disease in which there is a high level of sugar in the blood. Insulin is a hormone produced by the pancreas in your body to control this blood sugar. Diabetes thus, can be caused by too little insulin production, resistance to insulin, or both.
To understand diabetes, it is important to first understand the normal process by which food is broken down and used by the body for energy. Several things happen when food is digested:
A sugar called glucose is absorbed into the bloodstream. Glucose is a source of fuel for our body. The body now produces insulin. The role of this insulin is to move glucose from the bloodstream into muscle, fat, and liver cells, where it can be stored.Diabetics have high blood sugar because their body cannot move sugar into fat, liver, and muscle cells to be stored for energy.
Why does this happen?
Their pancreas either does not make enough insulin or the body cells do not respond to insulin normally.Both of the above ca also occur
There are three major types of diabetes:
Type 1 diabetes can occur at any age, but it is most often diagnosed in children, teens, or young adults. In this disease, the Glucofort body makes little or no insulin. Daily injections of insulin are needed to control this. The exact cause is unknown.
Type 2 diabetes makes up most of diabetes cases. It most often occurs in adulthood, but teens and young adults are now being diagnosed with it because of high obesity rates. Many people with type 2 diabetes do not know they have it. In this type of Diabetes the cells of the body require higher insulin levels to clear the blood of sugar
Gestational diabetes is high blood sugar that develops at any time during pregnancy in a woman who does not have diabetes.
Complications of Diabetes:
Periodontitis: Periodontitis is an infection of the supporting structures of the teeth ie, the Alveolar bone the ligaments and the gingiva on top. Uncontrolled diabetics show increased levels of gum infections which results in early loss of their teeth. In uncontrolled diabetics there is increased production of advanced glycation end products.these do not allow the collagen to be remodeled therefore the collagen tends to break down at the slightest infection resulting in multiple abscess in the gums
Diabetic cardiomyopathy: damage to the heart, leading to diastolic dysfunction and eventually heart failure.
Diabetic nephropathy: damage to the kidney which can lead to chronic renal failure, eventually requiring dialysis. Diabetes mellitus is the most common cause of adult kidney failure worldwide in the developed world.
Diabetic neuropathy: abnormal and decreased sensation, usually in a ‘glove and stocking’ distribution starting with the feet but potentially in other nerves, later often fingers and hands. When combined with damaged blood vessels this can lead to a diabetic foot. Other forms of diabetic neuropathy may present as mononeuritis or autonomic neuropathy. Diabetic amyotrophy is muscle weakness due to neuropathy.
Diabetic retinopathy: growth of friable and poor-quality new blood vessels in the retina as well as macular edema (swelling of the macula), which can lead to severe vision loss or blindness.
Is there an association between gum disease and Diabetes?
For the nearly 50 million Indians that have diabetes, many may be surprised to learn about Periodontitis being an unexpected complication associated with this condition. Research shows that there is an increased prevalence of advanced gum disease called periodontitis among those with diabetes, The American Diabetic Association has added periodontitis to the list of other 5 established complications associated with diabetes, macro vascular disease such as heart disease, micro-vascular diseases, retinopathy, nephropathy (renal disease) and neuropathy.
If I have gum disease like Periodontitis will I have more diabetes?
Research is showing that when gum disease/ periodontitis is present it results in increased levels of TNF-alpha. The ability of the body to respond to insulin decreases therefore the patient requires a higher dose of insulin or oral hypoglycemic drugs to control their rising blood sugar levels. Research has also shown that once this gum disease is controlled the amount of medication required reduces.